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Showing posts from July, 2025

California - cost and budget

An analysis of the annual cost of implementing “Free PGS for All” in California, compared to the state’s overall budget: --- 1. 🧠 California’s Annual Budget (2025–26) Total State Spending (general fund + special funds): ≈ $322 billion   Health & Human Services (HHS) budget alone: ≈ $283.9 billion total (includes federal funds)   Behavioral Health (mental health): MHSA “state‑directed” spending: ~$153 million   Plus new $6.38 billion bond for behavioral health infrastructure (Prop 1; spread over years)   --- 2. 💵 Estimated Annual Cost for Free PGS Let’s run a plausible pilot model: IVF cycles/year in CA: ~30,000 Cost per PGS + counseling: $10,000 Annual cost: 30,000 × $10,000 = $300 million Expanding to broader prevention (including non-IVF early risk screening) might double it: Estimated total annual program cost: $500 million–$1 billion --- 3. ⚖️ Comparison to Existing Budgets Category Annual Cost (approx.) PGS for IVF (state‑wide) $300 mil...
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Singapore - cost and budget

An analysis estimating the annual cost of implementing free PGS-based mental illness prevention in Singapore, and how that compares with the nation’s annual budget: --- 🇸🇬 1. Singapore’s 2025 Annual Budget Overview Total government expenditure (FY2025): S$123.8 billion (~US$92 billion)   Operating expenditure: S$97.0 billion; development expenditure: S$26.8 billion   Health ministry spending: ~S$20.9 billion (~17% of ministry expenditure)   Mental health expenditure: about 3% of healthcare budget, around S$434.6 million in 2022   --- 2. Estimated Annual Cost for Free PGS in Singapore 🧪 Scenario A: IVF‑based PGS Access Estimated IVF cycles/year in Singapore: 5,000 (a mix of local and foreign usage) Cost per PGS + counseling: ~S$14,000 (USD USD equivalent ~10 000) Total cost: 5,000 × S$14,000 = ~S$70 million per year 🌐 Scenario B: Expanded Screening (IVF + Early Risk Screening) Includes early-life embryo or child risk screening Estimated cost ra...
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Chronic mental disorders worldwide

Approximately 970 million people worldwide, or about 1 in every 8 people, live with a mental disorder ¹. This number includes various chronic mental health conditions, such as: - *Anxiety Disorders*: 301 million people, with 58 million being children and adolescents ¹ - *Depressive Disorders*: 280 million people, with 23 million being children and adolescents ¹ - *Bipolar Disorder*: 40 million people ¹ - *Schizophrenia*: 24 million people, or about 1 in 300 people worldwide ¹ - *Eating Disorders*: 14 million people, with almost 3 million being children and adolescents ¹ It's essential to note that these numbers are likely underestimates, as many cases go unreported or undiagnosed. Additionally, people with chronic mental health conditions often face increased risks of developing other chronic diseases, such as heart disease, diabetes, and obesity ² ³.
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Likely religious opposition

Summary Table | Region          | Pop (approx.) | Opposed Count | Percent Opposed | |----------------|----------------|----------------|------------------| | UK             | ~67M           | ~30M           | ~45%             | | Sweden         | ~10.4M         | ~5.1M          | ~49%             | | Austria        | ~9M            | ~5.6M          | ~62%             | | Japan          | ~125M          | ~31M           | ~25%             | | Massachusetts  | ~6.9M          | ~...
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Public Policy Proposal

🏛️ Public Policy Proposal: Preconception Genetic Selection for Future Mental Health A Policy Framework to Prevent Inherited Mental Suffering While Respecting Life and Ethics --- 🧠 1. Policy Title "The Compassionate Conception Act" Using science to prevent suffering, without destroying embryos. --- 🎯 2. Objective To reduce the incidence of severe inherited mental health conditions by providing voluntary, ethical preconception genetic screening and gamete selection, funded and regulated by the state. --- 🧬 3. Core Principles Compassion: Prevent inherited suffering before it begins Respect for Life: No embryo destruction; selection occurs before conception Voluntary Participation: No coercion — only informed, parent-led choices Equality: Universal access regardless of income, race, or religion Transparency and Oversight: Ethics boards and public reporting --- 🧩 4. Program Components A. Preconception Genetic Screening Offer free or subsidized full-genome sequencing of parent...
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